4 Minute CBD Oil Quiz & Survey



Approximately 54 million adults and 300,000 children in the U.S. have been diagnosed with arthritis or some other type of rheumatic disease, according to the Arthritis Foundation (AF).

If you consider all of the individuals who have arthritis but have not yet been diagnosed, the AF suggests that the true count is likely closer to 91.2 million in total. What’s worse is that the number is expected to grow by 49 percent by the year 2040.

A few of the most problematic symptoms associated with arthritis include pain, stiffness, and movement issues within the joints, all of which can be severe with RA and worsen over time. Yet there are other symptoms that are just as troublesome, such as anxiety and depression. Not only that, but it can become especially trying when you have to contend with other health conditions that tend to coexist with arthritis, like heart disease, diabetes, and obesity.

Some medications and treatment programs can potentially help ease these negative effects, but many people are searching for a more natural pain relief option. This is where CBD oil comes into play.

What is CBD Oil?

CBD is short for cannabidiol, which MedlinePlus explains is one of more than 80 chemical cannabinoids found in the marijuana plant Cannabis sativa. Thus, cannabis oil, or CBD oil as it is more commonly known, is oil that is developed using this particular compound.

Although CBD oil is just now becoming fairly mainstream, largely because of the debates surrounding medical marijuana, cannabis actually has a long history of providing relief in many different places around the world.

CBD’s Long History

In June 2015, National Geographic ran a story about how Siberian burial mounds as far back as 3000 B.C. were found to contain charred cannabis seeds. Cannabis has also been used in Chinese medicine for thousands and thousands of years.

The article went on to explain how American use of cannabis goes back to our country’s founding fathers as well. In fact, George Washington himself grew hemp at his plantation estate and the location of his burial, Mount Vernon.

However, because marijuana has been declared illegal for use, research on its positive properties has been extremely limited. This has caused many people to question its use for modern-day ailments, primarily because they don’t know a lot about how it works. They also don’t realize that the human body actually produces its own cannabinoids too.

How Cannabis Oil Works

According to Medical News Today, the body has two cannabinoid receptors: CB1 and CB2.

  • A majority of CB1 receptors are located in the brain and are associated with cognitive actions related to coordination, mood, thinking, memory, and appetite.
  • The CB2 receptors, on the other hand, can be found in the immune system. This makes them more responsible for the body’s response to pain and inflammation.

Tetrahydrocannabinol, or THC, attaches to the CB1 receptors, which explains why smoking or otherwise ingesting marijuana affects users on a cognitive level.

However, CBD impacts the CB2 receptors instead. And it does so indirectly, not by attaching to the CB2 receptor, but by enticing the body to make more of its own cannabinoids. This creates a positive effect on the body’s pain and inflammation responses.

Benefits of CBD Oil

Many studies have been conducted on CBD and found that this compound offers individuals diagnosed with RA many potential benefits.

CBD Oil Eases Arthritis Pain

One of the primary CBD oil benefits for rheumatoid arthritis sufferers is its positive effect on pain, and research confirms it.

A study published in the journal Pain in December 2017 analyzed whether CBD could prevent osteoarthritis pain and joint neuropathy. Based on their findings, researchers affirmed that it did both, because it decreased joint inflammation and served as a protectant to the nerves.

CBD Oil Relieves Other Chronic Pain Conditions

CBD oil has been found to relieve other chronic pains as well. Research published in Therapeutics and Clinical Risk Management indicates that cannabinoids have been helpful with easing pain for individuals diagnosed with conditions such as multiple sclerosis and cancer.

Other studies have reported positive effects for individuals taking CBD to ease their fibromyalgia pain.

CBD Oil and Anxiety

CBD oil has also been linked to a variety of mental health benefits, such as a reduction in anxiety. Research suggests that it is so effective in this regard that it has “considerable potential as a treatment for multiple anxiety disorders.” One study published in The Permanente Journal even found that CBD oil can help reduce anxiety in young children.

CBD Oil for Depression

Several studies have also linked CBD to a reduction of symptoms associated with depression. This is extremely important because as the Arthritis Foundation says that the depression rates of those diagnosed with certain types of arthritis “can be between two- and ten-times greater than the rates of the general population.”

Is CBD Oil Legal?

Although CBD oil has a number of potential benefits, one of the top questions that individuals diagnosed with rheumatoid arthritis have is whether or not it is legal. Answering this question requires some understanding of certain components of the marijuana plant.

The compound in the cannabis plant that is most well-known is THC. This is the chemical responsible for marijuana’s notorious high. However, unlike THC, cannabidiol does not have psychoactive properties. This means that it does not create the same effect that one normally gets when smoking, inhaling, or otherwise ingesting marijuana.

Furthermore, the U.S. Drug Enforcement Administration (DEA) says that it is the THC that makes marijuana illegal in a number of different states. That’s why people with RA have great concern when deciding whether or not to use CBD oil, a derivative of the same plant yet a totally different compound, to help ease their pain.

As a result, the answer to “Is CBD oil legal?” isn’t quite so clear.

While marijuana itself is illegal on a federal level, many states have adopted their own laws to create some level of legal use. For instance, some states allow the consumption of marijuana and its extracts only for medical reasons, which makes a medical marijuana card necessary for its use. Some states have approved this drug and its components for recreational use as well.

To make matters more complex, on December 14, 2016, the DEA issued a Final Rule that created a new code number (7350) designed to cover “any material, compound, mixture, or preparation” surrounding the marijuana plant. Upon clarification of this new code, the DEA indicated that CBD extracts that contains even small amounts of other cannabinoids would still fall under the old code, making them illegal under federal rule. However, CBD extracts that contain no other cannabinoids would fall under the new code, where they could potentially be legal to use.

Plus, some CBD oils are derived from hemp, the fiber of the cannabis plant. The 2014 Farm Bill declares certain hemp cultivation practices legal, muddying the legal waters even more.

In short, to determine whether a CBD oil or any other CBD product is legal or illegal depends on a multitude of factors. Your geographical location, local laws, and whether there are any other cannabinoids in the extract must all be taken into consideration before arriving at a final answer.

Is CBD Oil Safe?

The second most common question people have when it comes to CBD oil is whether or not it is safe. According to some top health experts and agencies, the answer is yes.

For instance, Medscape shares that while cannabinoid medicine is still in its early stages, “unlike marijuana and THC, the risks associated with CBD are extremely low, with not a single case report of CBD overdose in the literature.

The National Institute on Drug Abuse agrees and states that “CBD appears to be a safe drug with no addictive effects.”

Potential Risks of CBD Oil

Many health experts have deemed CBD safe to use, but like with any substance, there does appear to be a few potential risks when it comes to using this extract.

Medication/Drug Interactions

MedlinePlus indicates that CBD can sometimes interact with certain prescription medications, primarily those that are “changed and broken down by the liver.”

These include, but are not limited to common medications such as:

  • ondansetron (Zofran)
  • clozapine (Clozaril, FazaClo)
  • progesterone (Endometrin, Prometrium)
  • testosterone
  • disulfiram (Antabuse)
  • ketamine (Ketalar)
  • phenobarbital (Luminal)
  • omeprazole (Prilosec)
  • lansoprazole (Prevacid)
  • diazepam (Valium)
  • carisoprodol (Soma)
  • ibuprofen (Motrin)
  • celecoxib (Celebrex)
  • amitriptyline (Elavil)
  • warfarin (Coumadin)
  • codeine
  • paroxetine (Paxil)
  • tramadol (Ultram)
  • venlafaxine (Effexor)
  • alprazolam (Xanax)
  • fexofenadine (Allegra)
  • benzodiazepines
  • morphine

MedlinePlus further states that there are other “drugs” that can potentially interact with CBD as well, including caffeine and nicotine. However, research has not necessarily supported these claims.

For instance, a 2015 study published in the journal Pharmacology Biochemistry and Behavior found that, in the right dose, caffeine can actually potentially help prevent CBD effects on memory.

Another piece of research, this one published in the Addictive Behaviors journal, found that CBD “significantly reduced” (as much as 40 percent) the number of cigarettes smoked by individuals who wanted to quit.

CBD and Drowsiness

Another potential risk of CBD is that it can cause drowsiness. Therefore, if you’re taking supplements or medications to help you sleep, CBD could enhance these effects even more. It’s important to keep this in mind if you’re performing activities that require maximum alertness, such as driving or operating heavy machinery.

CBD Dosing Considerations

If you’re interested in using CBD oil to help ease your rheumatoid arthritis pain, you may be wondering how much to administer or apply. However, when talking about proper CBD dosing, it’s important to first understand bioavailability.

CBD Bioavailability

Bioavailability is defined as the “amount of a substance that becomes available (reaches the target organ or system circulation) to an organism’s body for bioactivity when introduced through ingestion, inhalation, injection, or skin contact.” In short, it is how much of the substance your body can effectively use based on the type taken.

In the case of CBD oil specifically, Medscape shares that while intranasal administration of CBD has a bioavailability of 34 to 46 percent and CBD vaporization has 40 percent bioavailability, “oral CBD is thought to be as low as 6 percent, owing to significant first pass-metabolism.”

First-Pass Metabolism and CBD

An article published in the journal Nurse Prescribing explains that first-pass metabolism occurs in the gut or the liver and is when some of the drug is destroyed before it is able to be circulated around the body. Thus, based on the research above, taking CBD oil in pill form may mean that your body only receives as little as 6 percent of the CBD.

Another option is to take CBD oil topically, either alone or as part of a lotion or cream. Research published in the European Journal of Pain studied the effectiveness of this approach and found that “topical CBD application has therapeutic potential for relief of arthritis pain-related behaviours and inflammation without evident side-effects.”

Proper CBD Dosing

Because CBD is so new, Medscape recommends that users “start low, go slow.” This enables you to see how well your body responds without giving it more than the necessary amount.

Plus, there are no governmental regulations regarding the manufacture and sale of CBD, so you never know if you’re getting the amount actually listed on the label. This makes erring on the side of caution even more important.

CBD Oil Options

Consumer Health Digest (CHD) published The Best CBD Oil Products of 2018 and, according to this guide, the three most important terms to know before purchasing your CBD oil are CBD volume, hemp oil volume, and CBD concentration. The second and third are the most critical, according to CHD, because they indicate the oil’s potency.

It’s also important to realize that there are different product options with regard to CBD oils. They are:

  • CBD oil, which is the “more potent version and delivery system of CBD”
  • CBD oil topical solutions, enabling the user to use it on a more targeted area
  • CBD oil tinctures, which are alcohol-based cannabis extracts that can be ingested orally, and the most popular CBD oil choice
  • CBD dietary supplements, or capsules containing CBD oil in in a powdered form

The one you choose will depend largely on the location and severity of your pain. If you want to target a specific area, an oil or oil topical may be the best. However, if the pain is all over, then a tincture or dietary supplement may provide the most relief.

CHD’s guide goes on to share that the three top-rated CBD oil products on the shelves today are Blue Label High CBD Hemp Oil (Herbal Renewals), CBD Oil Herbal Spray (Herbal Renewals), and Vaporizer Kit (G1).

Also, if you’re new to using CBD oil, CHD further recommends that you start with 1 to 3 milligrams per day.